Are you the type of person who finds what is likely a very begin unidentified bump on your skin and immediately takes off on a quest into WebMD to make sure you're not dying? If so, this probably isn't the list for you. These are the most terrifying, bizarre, and misunderstood medical conditions that you can get, and the worst part is: most of them still have no cure.
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Possibly one of the most terrifying medical conditions that exists, locked in syndrome refers to a condition in which a patient is unable to move any part of their body except their eyes.
Despite not being able to move or speak, the patient is completely conscious and is aware that they are unable to move. Locked in syndrome can be brought on by stroke, poisoning, traumatic brain injury, or drug overdose.
Some patients are able to communicate with coded messages through blinks and eye movement, that is, if anyone notices they are even awake.
It often takes up to three months before patients are recognized as having locked in syndrome and not just being unconscious or in a coma.
Currently, there is no cure and patients rarely recover.
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Fibrodysplasia ossificans progressiva is a genetic disorder that causes the body to repair damaged tissue with bone.
Basically, over time this disease will turn all of someone’s soft tissue such as muscles, tendons, and ligaments into bone.
Not only is there no cure for fibrodysplasia ossificans progressiva, any attempts doctors have made to remove the bone formations in patients have resulted in the body producing even more bone in its place.
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Trigeminal neuralgia is a condition in which patients experience bursts of excruciating face pain caused by disruption to the trigeminal nerve, which connects your face to your brain.
The pain can be brought on by just about anything: teeth brushing, eating, speaking, or even just smiling.
The episodes can last anywhere from a few seconds to days and patients have compared the pain to getting a severe electric shock to the face.
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Kleine–Levin syndrome is a disorder in which patients sleep excessively, sometimes for days at a time.
Patients can also develop excessive hunger and hyper-sexuality. Episodes can last for anywhere for a few days to weeks.
It’s not known what causes Kleine–Levin syndrome, but it is often brought on in adolescents after a severe fever or flu.
There is currently no cure, but doctors have been able to effectively treat the symptoms with lithium and anti-psychotics.
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It’s not exactly dinner table conversation, but everyone gets diarrhea every once and awhile.
Just a single bought of loose stools can be pretty terrible, but imagine having Brainerd diarrhea: uncontrollable diarrhea that lasts for weeks or even months.
As if that isn’t bad enough, patients with Brainerd diarrhea not only have a long onset of diarrhea but have it up to 20 times a day.
The worst part: nobody is sure what causes it and it often breaks out in communities where everyone gets it at once. Hopefully, your town isn’t next.
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>Complex Regional Pain Syndrome usually results from an injury like a broken bone or fracture, or after a major medical event like a heart attack or stroke.
A patient who has Complex Regional Pain Syndrome experiences excruciating pain, normally in an extremity like an arm or leg, that is out of portion with the initial injury.
There can also be swelling, skin discoloration, muscle loss, and even the loss of the ability to use the affected limb.
It can even spread from one limb to another, even if the other limb was healthy before.
But the weirdest thing about CRPS? Nobody knows what causes it. While it is usually observed after a medical event, it’s not clear why people’s bodies react this way, even after the initial injury is healed.
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Cyclic vomiting syndrome is exactly what is sounds like: a disease that causes a person to vomit uncontrollably, for hours on end, with no apparent cause like a cold or virus. Just vomit for no reason, basically.
This affects mostly children ages 3-7 and some people think it is associated with migraines.
Many people who have migraines can tell you that vomiting is often on the migraine menu along with a headache, so it makes sense.
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Steven Johnson Syndrome causes the patient’s skin to blister and then peel away from the body.
People with Steven Johnson Syndrome look as though their body has been burned by a fire.
It’s incredibly rare but is usually a reaction to a medication.
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Labyrinthitis is an infection of the inner ear that causes intense vertigo, hearing loss, and a ringing in your ears.
Vertigo refers to a feeling of spinning, that can be so intense in labyrinthitis patients, they can throw up.
Labyrinthitis is often brought on by a cold or infection and can last weeks.
That’s weeks of feeling like you’re on a carnival ride that won’t stop.
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People with aquagenic urticaria get hives whenever water touches their skin.
That’s right, some people (a very, very small number of people) are basically allergic to water.
It’s not really an allergy, but doctors aren’t entirely sure what causes the reaction.
It’s so rare that there isn’t really a treatment for it, but doctors have found some success treating it with anti-histamines, steroids, and light treatment.
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Hemophilia is a disease in which the body has an inability or reduced ability to create blood clots.
When a person with hemophilia gets a cut, undergoes surgery, or has a dental procedure, they can’t stop bleeding for a long time.
Hemophilia can also cause internal bleeding, which can be very dangerous.
Hemophilia was once called “the royal disease” because European royalty suffered from it, as it is passed on genetically.
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Necrotizing fasciitis is a rapidly moving infection that results in tissue death.
AKA: people with necrotizing fasciitis are literally being eaten alive by bacteria.
Necrotizing fasciitis isn’t just one type of bacteria: it’s the name for any bacteria that can kill tissue quickly.
This most often results from bacteria entering a wound, in one case a girl had her leg amputated after contracting necrotizing fasciitis when she cut her leg going down a zipline. Other cases have come from patients with open wounds swimming in lakes, hot tubs, or other bodies of water.
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This disease will make your body grow scaly bumps and horn-like lesions, that often cluster on patient’s hands and feet. Because of these growths, people other think epidermodysplasia verruciformis patients look like they are half person, half tree.
Epidermodysplasia Verruciformis is not curable, although some people have gotten surgery to remove the growths, however, they always return.
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Harlequin-type ichthyosis is a genetic skin disorder, characterized by thick pieces of skin separated by deep cracks and eyelids that are flipped inside out.
Babies are born with Harlequin-type ichthyosis and have it all their lives and often don’t live long.
However, some adults have survived with the disorder.
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Hypertrichosis is a condition in which people grow an excessive amount of hair in places where hair doesn’t normally grow. So, like a werewolf. This condition can affect the entire body or just be localized to one area.
People with hypertrichosis were often put in freak shows in the past, where it was said that they were half man, half animal but now we know that it’s actually a genetic disorder.
Hypertrichosis cannot be treated, however many people choose to remove the hair, even though it can return within a matter of hours.
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Progeria is a genetic disorder that causes people to age rapidly.
Kids who are born with the disorder rarely live into their teens.
They quickly begin to develop symptoms that seem like that of an elderly person: wrinkled skin, joint pain, weakness, hair loss, and loss of eyesight. There is no cure for the disease.
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Cluster headaches are reoccurring, intense headaches on the side of the face that can last anywhere from 15 minutes to three hours.
They are said to be some of the worst pain imaginable, rating even above childbirth.
They come in clusters, which means people who get these terrible headaches experience them for weeks at a time with no relief and never know when they are going to strike again.
They have also been called “suicide headaches” for a pretty grim reason: some people have committed suicide as a last resort to stop these headaches.
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You know those throw pillows that say thing like “Remember to breathe”?
Well, people with central hypoventilation syndrome actually do. This disease makes people take very short, shallow breaths, which means they have to sleep with an oxygen mask on in case they don’t get enough oxygen.
They also can lose the ability to auto-breath, so they have to actively remember to take breaths or they will die.
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If you think you have bad insomnia, be glad it’s not fatal familial insomnia.
This disease affects the brain, like Mad Cow Disease. It results in insomnia to the point of never sleeping, hallucination, paranoia, and eventually death. There is no cure.
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